Invitrogen™ GANAB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521425

Catalog No. PIPA521425

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4. Predicted reactivity: Mouse (90%), Rat (89%), Pig (91%), Rhesus Monkey (97%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Specifications

• Antigen: GANAB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ganab
• Gene Alias: alpha glucosidase 2 alpha neutral subunit; alpha-glucosidase 2; AU042638; carbohydrate processing enzyme of the endoplasmic reticulum; G2an; GANAB; GIIA; glucosidase II alpha subunit; glucosidase II alpha-subunit; glucosidase II subunit alpha; glucosidase, alpha; neutral AB; GLUII; KIAA0088; mKIAA0088; neutral AB; neutral alpha-glucosidase AB
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23193
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.03 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14697
• Gene Symbols: Ganab
• Immunogen: Recombinant fragment corresponding to a region within amino acids 654 and 944 of alpha Glucosidase II (Uniprot ID#Q14697).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov