Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

GAPDHS mouse anti-Human, Mouse, Rat, Clone: 1D4, Invitrogen™

mouse Monoclonal Antibody

Manufacturer:  Thermo Scientific MA533106

Catalog No. PIMA533106


Add to cart

Description

Description

Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. Because GAPDH is a protein expressed in large amounts and which is required at all times for important "house keeping" functions, levels of GAPDH mRNA are often measured and used as standards in studies of mRNA expression. Increasingly, scientists are making use of specific antibodies to GAPDH in comparable studies of levels of protein expression. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer′s disease, and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington′s disease. Associations with actin and tubulin have also been reported. The protein may also have a role in the regulation of apoptosis, and interestingly migrates from the cytoplasm into the nucleus when cells become apoptotic.
Specifications

Specifications

GAPDHS
Monoclonal
1 mg/mL
PBS with 10mM sodium azide
O14556, Q64467, Q9ESV6
GAPDHS
Purified porcine GAPDH
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Immunofluorescence, Immunohistochemistry, Western Blot
1D4
Unconjugated
GAPDHS
Liquid
Mouse
IgM
100 μL
-20°C
Primary
14447, 26330, 66020
SDS
Documents
Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit