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GAPDHS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 139371AP150UL

Encompass_Preferred

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Catalog No. 50-172-9104


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Description

Description

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), also called uracil DNA glycosylase, catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. While GAPDH has long been recognized as playing an integral role in glycolysis, additional functions of GAPDH include acting as a uricil DNA glycosylase, activating transcription, binding RNA and involvement in nuclear RNA export, DNA replication and DNA repair. Expression of GAPDH is upregulated in liver, lung and prostate cancers. GAPDH translocates to the nucleus during apoptosis. GAPDH complexes with neuronal proteins implicated in human neuro-degenerative disorders including the beta-Amyloid precursor, Huntingtin and other triplet repeat neuronal disorder proteins.
Specifications

Specifications

GAPDHS
Polyclonal
Unconjugated
GAPDHS
GAPD2, GAPDH 2, GAPDH2, GAPDHS, GAPDS, HSD 35
Rabbit
Antigen Affinity Chromatography
RUO
14447, 26330, 66020
-20°C
Liquid
Western Blot
0.43 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14556, Q64467, Q9ESV6
Gapdhs
GAPDHS Fusion Protein Ag4988
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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