Invitrogen™ GASP1 Monoclonal Antibody (288518)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523990

Catalog No. PIMA523990

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human GASP-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A. The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence, and multiple identifiable structural features, including a WAP domain, a follistatin/Kazal domain, an immunoglobulin domain, two tandem Kunitz domains, and a netrin domain.

Specifications

• Antigen: GASP1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q8TEU8
• Gene Symbols: WFIKKN2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human GASP-1/WFIKKNRP Leu35-His576.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry
• Clone: 288518
• Conjugate: Unconjugated
• Gene: WFIKKN2
• Gene Alias: 2610304F08Rik; AY100450; Gasp1; GASP-1; Growth and differentiation factor-associated serum protein 1; hGASP-1; mGASP-1; multivalent protease inhibitor protein; RGD1305361; UNQ9235/PRO31996; WAP four-disulfide core domain 20B; WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein; WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; WAP, FS, Ig, two KU and NTR module related protein; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2; WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2; WFDC20B; WFIKKN2; WFIKKN-related protein; WFIKKNRP
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 124857
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized