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Gastrokine 1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983274
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50-198-3274 100 μL
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Catalog No. 50-198-3274 Supplier Bioss Supplier No. BS14441R
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Description

Rabbit Polyclonal Antibody

Gastrokine 1, also known as GKN1 and CA11, is a 185 amino acid containing secreted protein belonging to the gastrokine family with a BRICHOS domain and an asn-rich region. GKN1 (also known as an antioncogene) is reported to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa. Differential display of normal and cancerous gastric tissue suggested that this protein is predominantly expressed in stomach and the expression is down-regulated to considerable frequency in cancer tissue or gastric cancer cell lines examined. This extra cellular protein is co-secreted with mucins and is a signaling growth factor with mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.

Specifications

Antigen Gastrokine 1
Applications Immunofluorescence, Immunohistochemistry (Frozen)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GKN1
Gene Accession No. Q9NS71
Gene Alias 18 kDa antrum mucosa protein; 2200002K21Rik; AMP18; AMP-18; BRICD1; BRICHOS domain containing 1; CA11; FOV; foveolin; gastrokine 1; Gastrokine-1; Gkn1; Protein CA11; Protein CA11 homolog; UNQ489/PRO1005
Gene Symbols GKN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Gastrokine 1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56287
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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