Invitrogen™ GATA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529736

Catalog No. PIPA529736

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116, H1299. Predicted reactivity: Mouse (97%), Rat (96%), Xenopus laevis (87%), Pig (99%), Chicken (86%), Bovine (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.

Specifications

• Antigen: GATA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GATA2
• Gene Alias: DCML; EMBL:AAK51128.1}; Endothelial transcription factor GATA-2; FLJ45948; GATA binding protein 2; GATA binding protein 3; GATA2; Gata-2; gata2 {ECO:0000312; GATA3; GATA-binding factor 3; GATA-binding protein 2; GATA-bindning protein 2; HDR; HDRS; IMD21; MGC2306; MONOMAC; NFE1B; trans-acting T-cell-specific transcription factor GATA-3; uterine GATA-4 transcription factor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14461, 25159, 2624
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 0.38 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O09100, P23769, Q924Y4
• Gene Symbols: GATA2
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 130 and 397 of Human GATA2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov