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Invitrogen™ GATA2 Recombinant Superclonal™ Antibody (11HCLC)

Catalog No. PI710242
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100 μg
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Catalog No. Quantity
PI710242 100 μg
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Catalog No. PI710242 Supplier Invitrogen™ Supplier No. 710242
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Description

Rabbit Recombinant Superclonal Antibody

This antibody is predicted to react with equine, non-human primate, mouse, rabbit and rat based on sequence homology. Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called 'Recombinant polyclonal antibody', this product is now rebranded as 'Recombinant Superclonal™ antibody'. The physical product and the performance remain unchanged.

GATA2 (GATA binding protein 2) belongs to the GATA family of transcription factors. GATA proteins play a very important role in signaling pathways controlling proliferation and differentiation of erythroid progenitor cells. There are 6 transcription factors in the GATA family: GATA1 to GATA6. GATA2 is a transcriptional activator regulating endothelin-1 gene expression in endothelial cells. It also appears to be involved in differentiation of other tissue types (uro-genital and nervous) during embryogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GATA2
Applications Western Blot, Immunocytochemistry
Classification Recombinant Superclonal
Clone 11HCLC
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2-7.4
Gene GATA2
Gene Accession No. P23769
Gene Alias DCML; EMBL:AAK51128.1}; Endothelial transcription factor GATA-2; FLJ45948; GATA binding protein 2; GATA binding protein 3; GATA2; Gata-2; gata2 {ECO:0000312; GATA3; GATA-binding factor 3; GATA-binding protein 2; GATA-bindning protein 2; HDR; HDRS; IMD21; MGC2306; MONOMAC; NFE1B; trans-acting T-cell-specific transcription factor GATA-3; uterine GATA-4 transcription factor
Gene Symbols GATA2
Host Species Rabbit
Immunogen Peptide corresponding to amino acids 396-409 of human GATA binding protein 2.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100008832, 2624
Target Species Human, Rabbit
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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