Learn More
GATA3 Mouse anti-Human, Clone: OTI10G7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF809219

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. The human gene comprises 6 exons distributed over 17 kb of DNA. Its 2 zinc fingers are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells or macrophages.Specifications
GATA3 | |
Monoclonal | |
Unconjugated | |
GATA3 | |
HDR, HDRS | |
Mouse | |
Affinity Chromatography | |
RUO | |
2625 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI10G7 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P23771 | |
GATA3 | |
Human recombit protein fragment corresponding to amino acids 155-443 of human GATA3 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2b |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.