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Invitrogen™ GATA6 Monoclonal Antibody (6H8)
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Catalog No. PIMA532961
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Quantity:
100 μL
Catalog No. Quantity
PIMA532961 100 μL
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Catalog No. PIMA532961

Supplier: Invitrogen™ MA532961

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Description

Mouse Monoclonal Antibody

Purity is > 95% by SDS-PAGE.

The GATA6 gene encodes a member of the GATA family of zinc-finger transcription factors, which are critical in regulating gene expression during development. GATA6 plays a crucial role in the differentiation and development of multiple tissues, including the heart and gastrointestinal tract, by interacting with other transcriptional regulators through its zinc-finger domains. This gene influences signaling pathways that drive epithelial-to-mesenchymal transitions (EMTs) and immune surveillance, which are essential processes in maintaining tissue homeostasis and countering tumor progression. In the respiratory tract, GATA6 is essential for the differentiation of lung epithelial cells, impacting the expression of WNT7B and surfactant proteins, vital for proper lung function. Furthermore, studies suggest that GATA6 contributes to an immune-enriched phenotype linked to favorable prognostic outcomes in certain cancers, indicating its potential role in mitigating metastatic propensity by enhancing immune response and surveillance against tumorous cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GATA6
Applications Western Blot
Classification Monoclonal
Clone 6H8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene GATA6
Gene Accession No. Q92908
Gene Alias AA410133; ASD9; AVSD5; DNA-binding protein GATA-GT2; GATA binding protein 6; Gata6; GATA-6; GATA-binding factor 6; GATA-binding protein 6; LOW QUALITY PROTEIN: transcription factor GATA-6; transcription factor GATA6; transcription factor GATA-6; zinc-finger transcription factor
Gene Symbols GATA6
Host Species Mouse
Immunogen Recombinant full length Human GATA-6.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2627
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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