Invitrogen™ GATAD2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113092

Catalog No. PIPA5113092

Description

GATAD2A Polyclonal Antibody for Western Blot, IHC (P), ELISA

GATAD2A is a gene encoding a protein that functions as a subunit of the nucleosome remodeling and deacetylase (NuRD) complex, which plays a crucial role in chromatin remodeling and gene expression regulation. Located on the human chromosome, GATAD2A contains proline-rich PPPL theta motifs that facilitate interactions with MYND domains in proteins such as ZMYND8, distinguishing it from its paralog GATAD2B. This gene is important for various cellular processes, particularly during neural development, where it participates in modulating chromatin structure through histone deacetylation and ATP-dependent remodelings, like those mediated by NuRD. Moreover, GATAD2A has been implicated in certain neurodevelopmental disorders, suggesting its distinct functional roles in cellular contexts. Additionally, research has identified circular RNA variants of GATAD2A, which have been shown to influence viral replication, indicating its broader impact on cellular function beyond chromatin modification.

Specifications

• Antigen: GATAD2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GATAD2A
• Gene Alias: 1110066C11Rik; BC031407; C80248; GATA zinc finger domain containing 2A; GATA zinc finger domain-containing protein 2A; GATAD2A; Hp66alpha; MGC29315; MGC36975; p66 alpha; p66a; p66alpha; RGD1310596; transcriptional repressor p66 alpha; Transcriptional repressor p66-alpha
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 290669, 54815
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.85 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q86YP4
• Gene Symbols: GATAD2A
• Immunogen: Recombinant Human Transcriptional repressor p66-alpha protein (170-241AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG