GBA Mouse anti-Human, Clone: OTI4G4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF803377

Catalog No. 50-166-6458

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

GBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: GBA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: GBA
• Gene Alias: GBA1, GCB, GLUC
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2629
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4G4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P04062
• Gene Symbols: GBA
• Immunogen: Human recombit protein fragment corresponding to amino acids 40-315 of human GBA produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a