Invitrogen™ GBA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530782

Catalog No. PIPA530782

Description

Recommended positive controls: 293T, A431, Jurkat. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.

Specifications

• Antigen: GBA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBA3
• Gene Alias: CBG; CBGL1; Cytosolic beta-glucosidase; cytosolic beta-glucosidase-like protein 1; Cytosolic GCase; Cytosolic glycosylceramidase; Gba3; GLUC; Glucosidase beta acid 3; glucosidase, beta, acid 3; glucosidase, beta, acid 3 (cytosolic); Glucosylceramidase beta 3; glucosylceramidase beta 3 (gene/pseudogene); klotho-related protein; KLRP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57733
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.55 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9H227
• Gene Symbols: GBA3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GBA3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG