Invitrogen™ GBA3 Recombinant Rabbit Monoclonal Antibody (008)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA529284

Catalog No. PIMA529284

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human GBA3.

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides. GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism.

Specifications

• Antigen: GBA3
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q9H227
• Gene Symbols: GBA3
• Immunogen: Recombinant Human GBA3 protein (Met1-Leu469).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: 008
• Conjugate: Unconjugated
• Gene: GBA3
• Gene Alias: CBG; CBGL1; Cytosolic beta-glucosidase; cytosolic beta-glucosidase-like protein 1; Cytosolic GCase; Cytosolic glycosylceramidase; Gba3; GLUC; Glucosidase beta acid 3; glucosidase, beta, acid 3; glucosidase, beta, acid 3 (cytosolic); Glucosylceramidase beta 3; glucosylceramidase beta 3 (gene/pseudogene); klotho-related protein; KLRP
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 57733
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid