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Invitrogen™ GBL Monoclonal Antibody (211CT7.1.1)
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Catalog No. PIMA537512
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100 μL
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Catalog No. Quantity
PIMA537512 100 μL
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Catalog No. PIMA537512 Supplier Invitrogen™ Supplier No. MA537512
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Description

Mouse Monoclonal Antibody

GBL Monoclonal Antibody for Western Blot

G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GBL
Applications Western Blot
Classification Monoclonal
Clone 211CT7.1.1
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.09% sodium azide; pH 7.4
Gene MLST8
Gene Accession No. Q9DCJ1
Gene Alias 0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; GBL; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; mLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1
Gene Symbols MLST8
Host Species Mouse
Immunogen GBL recombinant protein.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56716
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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