Invitrogen™ GBP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521809

Catalog No. PIPA521809

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (80%), Rat (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

Specifications

• Antigen: GBP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GBP5
• Gene Alias: 5330409J06Rik; GBP5; GBP-5; Gbp5a; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate nucleotide binding protein 5; guanylate-binding protein 5; muGBP-5; UNQ2427/PRO4987
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 115362
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96PP8
• Gene Symbols: GBP5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 213 of GBP5 (Uniprot ID#Q96PP8).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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