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Invitrogen™ GBP5 Polyclonal Antibody
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Catalog No. PIPA583024
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100 μL
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PIPA583024 100 μL
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Catalog No. PIPA583024 Supplier Invitrogen™ Supplier No. PA583024
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Rabbit Polyclonal Antibody

Immunogen sequence: TDQALTETEK KKKEAQVKAE AEKAEAQRLA AIQRQNEQMM QERERLHQEQ VRQMEIAKQN WLAEQQKMQE QQMQEQAAQL STTFQAQNRS LLSELQHAQR TVNNDDPCVL L Highest antigen sequence indentity to the following orthologs: Mouse - 41%, Rat - 44%.

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GBP5
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GBP5
Gene Accession No. Q96PP8
Gene Alias 5330409J06Rik; GBP5; GBP-5; Gbp5a; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; guanylate binding protein 5; guanylate nucleotide binding protein 5; guanylate-binding protein 5; muGBP-5; UNQ2427/PRO4987
Gene Symbols GBP5
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GBP5. Recombinant protein control fragment (Product #RP-94338).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 115362
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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