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Invitrogen™ GCAP2 Polyclonal Antibody
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Catalog No. PIPA584255
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100 μL
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PIPA584255 100 μL
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Catalog No. PIPA584255 Supplier Invitrogen™ Supplier No. PA584255
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GQEFSWEEAE AAGEIDVAEL QEWYKKFVME CPSGTLFMHE FKRFFKVTDD EEASQYVEGM FRAFDKNG Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 90%.

Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCAP2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GUCA1B
Gene Accession No. Q9UMX6
Gene Alias BC018258; DKFZp686E1183; GCAP 2; GCAP2; GCAP-2; GCAP2 (retina); guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); guanylate cyclase-activating protein, photoreceptor 2; Guanylin 2; guanylyl cyclase-activating protein 2; GUCA 2; GUCA1B; GUCA2; Retinal guanylyl cyclase activator protein p24; RP48
Gene Symbols GUCA1B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GUCA1B. Recombinant protein control fragment (Product #RP-108413).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2979
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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