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GCAP2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501982789
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100 μL
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50-198-2789 100 μL
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Catalog No. 50-198-2789 Supplier Bioss Supplier No. BS13307R
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Description

Rabbit Polyclonal Antibody

Guanylate cyclase-activating proteins (GCAPs) are calcium binding proteins that belong to the calmodulin superfamily. GCAPs without calcium are responsible for activation of photoreceptor guanylate cyclase during light adaptation. Studies have shown that the addition or subtraction of Ca2+ results in major conformational changes and the activation/deactivation of GCAP-1 and GCAP-2. It has been demonstrated that both GCAP-1 and 2 act on guanylate cyclase similarly and have approximately 50% homology between the two forms. GCAP-1 is predominantly localized in the photoreceptor outer segments, while GCAP-2 is found in retina samples.

Specifications

Antigen GCAP2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GUCA1B
Gene Accession No. Q9UMX6
Gene Alias BC018258; BOS_21473; DKFZp686E1183; GCAP 2; GCAP2; GCAP-2; GCAP2 (retina); Guanylate cyclase activator 1B; guanylate cyclase activator 1B (retina); guanylate cyclase activator 1B-like; guanylate cyclase-activating protein, photoreceptor 2; Guanylin 2; Guanylyl cyclase-activating protein 2; GUCA 2; Guca1b; GUCA2; LOC100351008; Retinal guanylyl cyclase activator protein p24; RP48
Gene Symbols GUCA1B
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GCAP2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2979
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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