Invitrogen™ GCAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554214

Catalog No. PIPA554214

Description

Immunogen sequence: CLASRYGALV FMDECHATGF LGPTGRGTDE LLGVMDQVTI INSTLGKALG GASGGYTTGP GPLVSLLRQR ARPYLFSNSL PPAVVGCASK ALDLLMGSNT IVQSMAAKTQ RFRSKMEAAG FTISGA Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.

Specifications

• Antigen: GCAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gcat
• Gene Alias: 2-amino-3-ketobutyrate coenzyme A ligase; 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 2-amino-3-ketobutyrate-CoA ligase; AI526977; AKB ligase; aminoacetone synthase; aminoacetone synthetase; aminotransferase; glycine acetyltransferase; aminoacetone synthetase; KBL; GCAT; Glycine acetyltransferase; glycine C-acetyltransferase; glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase); KBL; Unknown (protein for MGC:139551)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23464
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75600
• Gene Symbols: Gcat
• Immunogen: Recombinant protein corresponding to Human GCAT. Recombinant protein control fragment (Product #RP-91481).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG