Invitrogen™ GCAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA569553

Catalog No. PIPA569553

Description

This target displays homology in the following species: Cow: 92%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.

Specifications

• Antigen: GCAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gcat
• Gene Alias: 2-amino-3-ketobutyrate coenzyme A ligase; 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 2-amino-3-ketobutyrate-CoA ligase; AI526977; AKB ligase; aminoacetone synthase; aminoacetone synthetase; aminotransferase; glycine acetyltransferase; aminoacetone synthetase; KBL; GCAT; Glycine acetyltransferase; glycine C-acetyltransferase; glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase); KBL; Unknown (protein for MGC:139551)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26912
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O88986
• Gene Symbols: Gcat
• Immunogen: synthetic peptide directed towards the middle region of human GCAT (aa 219-268).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov