Invitrogen™ GCAT Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590717

Catalog No. PIPA590717

Description

Immunogen sequence: KAHKYRYRHL DMADLEAKLQ EAQKHRLRLV ATDGAFSMDG DIAPLQEICC LASRYGALVF MDECHATGFL GPTGRGTDEL LGVMDQVTII NSTLGKALGG ASGGYTTGPG PLVSLLRQRA RPYLFSNSLP PAVVGCASKA LDLLMGSNTI VQSMAAKTQR FRSKMEAAGF TISGASHPIC PVMLGDARLA SRMADDMLKR GIFVIGFSYP VVPKGKARIR VQISAVHSEE DIDRCVEAFV EVGRLHGALP; Positive Samples: Mouse eye; Cellular Location: Mitochondrion, Nucleus.

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.

Specifications

• Antigen: GCAT
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gcat
• Gene Alias: 2-amino-3-ketobutyrate coenzyme A ligase; 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial; 2-amino-3-ketobutyrate-CoA ligase; AI526977; AKB ligase; aminoacetone synthase; aminoacetone synthetase; aminotransferase; glycine acetyltransferase; aminoacetone synthetase; KBL; GCAT; Glycine acetyltransferase; glycine C-acetyltransferase; glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase); glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase); KBL; Unknown (protein for MGC:139551)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23464, 26912, 366959
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.67 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O75600, O88986
• Gene Symbols: Gcat
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_0551061).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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