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GCH1 Mouse anti-Human, Clone: OTI2D12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF810248

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with maligt hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.Specifications
GCH1 | |
Monoclonal | |
Unconjugated | |
GCH1 | |
DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B | |
Mouse | |
Affinity Chromatography | |
RUO | |
2643 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI2D12 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P30793 | |
GCH1 | |
Full length human recombit protein of human GCH1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |
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