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Invitrogen™ GCK Monoclonal Antibody (13)
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Catalog No. PIMA530454
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100 μL
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Catalog No. Quantity
PIMA530454 100 μL
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Catalog No. PIMA530454 Supplier Invitrogen™ Supplier No. MA530454
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Glucokinase.

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCK
Applications ELISA
Classification Monoclonal
Clone 13
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene GCK
Gene Accession No. P35557
Gene Alias ATP:D-hexose 6-phosphotransferase; FGQTL3; GC kinase; Gck; Gk; GLK; Gls006; glucokinase; glucokinase (hexokinase 4); glucokinase variant 3; GLUKA; hexokinase 4; hexokinase D, pancreatic isozyme; hexokinase type IV; Hexokinase-4; hexokinase-D; HHF3; HK IV; HK4; HKIV; Hlb62; HXKP; LGLK; MEKKK 2; MODY2; RNGK2
Gene Symbols GCK
Host Species Mouse
Immunogen Recombinant Human Glucokinase Protein (Leu2-Gln465).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2645
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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