Invitrogen™ GCKR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527959

Catalog No. PIPA527959

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver. Predicted reactivity: Mouse (89%), Rat (90%), Dog (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Specifications

• Antigen: GCKR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gckr
• Gene Alias: FGQTL5; Gckr; GKRP; GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulator; Glucokinase regulatory protein; hexokinase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231103, 2646
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q14397, Q91X44
• Gene Symbols: Gckr
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GCKR. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG