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Invitrogen™ GCKR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530944

Catalog No. PIPA530944


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Description

Description

Recommended positive controls: mouse liver. Predicted reactivity: Mouse (92%), Rat (92%), Dog (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GCKR
Polyclonal
Unconjugated
Gckr
FGQTL5; Gckr; GKRP; GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulator; Glucokinase regulatory protein; hexokinase 4
Rabbit
Antigen affinity chromatography
RUO
231103, 2646
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q14397, Q91X44
Gckr
Recombinant fragment corresponding to a region within amino acids 1 and 214 of Human GCKR.
100 μL
Primary
Human, Mouse
Antibody
IgG
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