Invitrogen™ GCKR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566679

Catalog No. PIPA566679

Description

Immunogen sequence: EDWSSTFRQVA ERMQKMQEKQ KAFVLNPAIG PEGLSGSSRM KGGSATKILL ETLLLAAHKT VDQGIAASQR CLLEILRTFE RAHQVTYSQS PKIATLMKSV STSL Highest antigen sequence identity to the following orthologs - mouse 90%, rat 90%.

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Specifications

• Antigen: GCKR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gckr
• Gene Alias: FGQTL5; Gckr; GKRP; GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulator; Glucokinase regulatory protein; hexokinase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2646
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14397
• Gene Symbols: Gckr
• Immunogen: Recombinant Human GCKR. Recombinant protein control fragment (Product #RP-107327).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov