Invitrogen™ GCKR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575253

Catalog No. PIPA575253

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Specifications

• Antigen: GCKR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gckr
• Gene Alias: FGQTL5; Gckr; GKRP; GLRE; glucokinase (hexokinase 4) regulator; glucokinase regulator; Glucokinase regulatory protein; hexokinase 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231103, 25658, 2646
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.2
• Gene Accession No.: Q07071, Q14397, Q91X44
• Gene Symbols: Gckr
• Immunogen: Synthetic peptide corresponding to amino acids 196-245 of Human GCKR.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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