Invitrogen™ GCLC Recombinant Rabbit Monoclonal Antibody (0X1H3)

GCLC Recombinant Rabbit Monoclonal Antibody (ARC1065)

Supplier:  Invitrogen™ MA535522

Catalog No. PIMA535522

Description

GCLC Recombinant Monoclonal Antibody for Western Blot

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Specifications

• Antigen: GCLC
• Classification: Recombinant Monoclonal
• Concentration: 1.7 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P19468
• Gene Symbols: Gclc
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 538-637 of human GCLC (P48506).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 0X1H3
• Conjugate: Unconjugated
• Gene: Gclc
• Gene Alias: cb1049; D9Wsu168e; EGK_15023; fe36e11; gamma GCS-HS; gamma-ECS; Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase heavy subunit; GCL; Gclc; GCS; GCS heavy chain; Ggcs-hs; GLCL; GLCLC; GLCL-H; glutamate-cysteine ligase catalytic subunit; Glutamate--cysteine ligase catalytic subunit; glutamate-cysteine ligase, catalytic subunit; Glutamylcysteine gamma synthetase light chain; wu:fe36e11
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25283
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid