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GCLC Mouse anti-Human, Rat, Clone: OTI1A3, liquid, TrueMAB™
SDP

Catalog No. 501677060
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50-167-7060 100 μL
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Catalog No. 50-167-7060 Supplier OriGene Supplier No. TA507318
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Description

Mouse Monoclonal Antibody

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Specifications

Antigen GCLC
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene GCLC
Gene Accession No. P19468, P48506
Gene Alias GCL, GCS, GLCL, GLCLC
Gene Symbols Gclc
Host Species Mouse
Immunogen Full length human recombit protein of human GCLC produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25283, 2729
Target Species Human, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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