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GCLC Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728102 Shop All Proteintech Group Inc Products
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50-172-8102 150 μL
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Catalog No. 50-172-8102 Supplier Proteintech Group Inc Supplier No. 126011AP150UL
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Description

Rabbit Polyclonal Antibody

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Specifications

Antigen GCLC
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene GCLC
Gene Accession No. P19468, P48506, P97494
Gene Alias Gamma ECS, GCLC, GCS, GCS heavy chain, GLCL, GLCLC
Gene Symbols GCLC
Host Species Rabbit
Immunogen GCLC Fusion Protein Ag3252
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14629, 25283, 2729
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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