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Invitrogen™ GCLM Polyclonal Antibody
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Catalog No. PIPA592388
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100 μL
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PIPA592388 100 μL
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Catalog No. PIPA592388 Supplier Invitrogen™ Supplier No. PA592388
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Description

Rabbit Polyclonal Antibody

Positive Samples: ES-2, U-937, 22Rv1, U-251MG, Mouse liver Immunogen sequence: MGTDSRAAKA LLARARTLHL QTGNLLNWGR LRKKCPSTHS EELHDCIQKT LNEWSSQINP DLVREFPDVL ECTVSHAVEK INPDEREEMK VSAKLFIVES NSSSSTRSAV DMACSVLGVA QLDSVIIASP PIEDGVNLSL EHLQPYWEEL ENLVQSKKIV AIGTSDLDKT QLEQLYQWAQ VKPNSNQVNL ASCCVMPPDL TAFAKQFDIQ LLTHNDPKEL LSEASFQEAL QESIPDIQAH EWVPLWLLRY SVIVKSRGII KSKGYILQAK RRGS.

Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCLM
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Gclm
Gene Accession No. O09172, P48507, P48508
Gene Alias AI649393; gamma glutamylcysteine synthetase; gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Gclm; Gcmc; GCS light chain; Glclr; glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory; glutamate cysteine ligase, modifier subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; Glutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase, modifier subunit; GSC light chain; null
Gene Symbols Gclm
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human GCLM (NP_0020521).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14630, 2730, 29739
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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