GCLM Recombinant Rabbit Monoclonal Antibody (ARC0597), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA537836

Catalog No. PIMA537836

Description

Positive Samples: U2OS, HeLa, A-431 Immunogen sequence: LYQWAQVKPN SNQVNLASCC VMPPDLTAFA KQFDIQLLTH NDPKELLSEA SFQEALQESI PDIQAHEWVP LWLLRYSVIV KSRGIIKSKG YILQAKRRGS

Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.

Specifications

• Antigen: GCLM
• Classification: Recombinant Monoclonal
• Concentration: 1.25 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P48507
• Gene Symbols: Gclm
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 175-274 of human GCLM (P48507)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: ARC0597
• Conjugate: Unconjugated
• Gene: Gclm
• Gene Alias: AI649393; gamma glutamylcysteine synthetase; gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Gclm; Gcmc; GCS light chain; Glclr; glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory; glutamate cysteine ligase, modifier subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; Glutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase, modifier subunit; GSC light chain; null
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2730
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid