Invitrogen™ GCM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546717

Catalog No. PIPA546717

Description

Peptide sequence: HSGYPVTNFW RLDGNAIFFQ AKGVHDHPRP ESKSETEARR SAIKRQMASF Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism.

Specifications

• Antigen: GCM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GCM2
• Gene Alias: chorion-specific transcription factor GCMb; GCM motif protein 2; Gcm1; Gcm1-rs2; GCM2; Gcm-2; Gcmb; gcmB transcription factor; Gcm-rs1; glial cell missing-like protein; glial cells missing 2; glial cells missing homolog 2; glial cells missing homolog 2 (Drosophila); glial cells missing homolog b; glial cells missing transcription factor 2; glial cells missing-like protein 2; glide/gcm protein homolog; hGCMb; mero; merovingian; mGCMb; RP3-417M14.3; transcription factor glial cells missing-2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9247
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O75603
• Gene Symbols: GCM2
• Immunogen: Synthetic peptide directed towards the N-terminal of human GCM2 (aa 133-182).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG