GCN1L1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301843A

Catalog No. 50-156-1127

Description

The recommended shelf life for this product is 1 year from date of receipt.

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1beta.

Specifications

• Antigen: GCN1L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GCN1
• Gene Alias: GCN1 (general control of amino-acid synthesis 1, yeast)-like 1, GCN1 eIF2 alpha kinase activator homolog, GCN1 eIF-2-alpha kinase activator homolog, GCN1 general control of amino-acid synthesis 1-like 1, GCN1 general control of amino-acid synthesis 1-like 1 (yeast), GCN1L, GCN1L1, GCN1-like protein 1, general control of amino-acid synthesis 1-like protein 1, hsGCN1, KIAA0219, peroxisome proliferator activated receptor interacting complex protein, PRIC295, translational activator GCN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10985, 231659, 690632
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/ml
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: E9PVA8, Q92616
• Gene Symbols: Gcn1, Gcn1l1
• Immunogen: Between 2621 and 2671
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG