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GCN1L1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Bethyl Laboratories

Catalog No. 501561127
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50-156-1127 100 μL
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Catalog No. 50-156-1127 Supplier Bethyl Laboratories, Inc Supplier No. A301843A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1beta.

Specifications

Antigen GCN1L1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene GCN1
Gene Accession No. E9PVA8, Q92616
Gene Alias GCN1 (general control of amino-acid synthesis 1, yeast)-like 1, GCN1 eIF2 alpha kinase activator homolog, GCN1 eIF-2-alpha kinase activator homolog, GCN1 general control of amino-acid synthesis 1-like 1, GCN1 general control of amino-acid synthesis 1-like 1 (yeast), GCN1L, GCN1L1, GCN1-like protein 1, general control of amino-acid synthesis 1-like protein 1, hsGCN1, KIAA0219, peroxisome proliferator activated receptor interacting complex protein, PRIC295, translational activator GCN1
Gene Symbols Gcn1, Gcn1l1
Host Species Rabbit
Immunogen Between 2621 and 2671
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10985, 231659, 690632
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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