Gcn1l1 Rabbit anti-Human, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS13315R

Catalog No. 50-198-2795

Description

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1beta.

Specifications

• Antigen: Gcn1l1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: GCN1
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 10985

• Gene Symbol: GCN1
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q92616
• Gene Alias: 4932409G22; AL022764; eIF-2-alpha kinase activator GCN1; G431004K08Rik; GCN1; GCN1 (general control of amino-acid synthesis 1, yeast)-like 1; GCN1 eIF2 alpha kinase activator homolog; GCN1 eIF-2-alpha kinase activator homolog; GCN1 general control of amino-acid synthesis 1-like 1; GCN1 general control of amino-acid synthesis 1-like 1 (yeast); GCN1, eIF2 alpha kinase activator homolog; GCN1L; GCN1L1; GCN1-like protein 1; General control of amino-acid synthesis 1-like protein 1; HsGCN1; KIAA0219; mKIAA0219; peroxisome proliferator activated receptor interacting complex protein; PRIC295; Translational activator GCN1
• Immunogen: KLH conjugated synthetic peptide derived from human Gcn1l1.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human