Invitrogen™ GCN5 Monoclonal Antibody (2GC-2C11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3046

Catalog No. MA3046

Description

MA3-046 detects GCN5 in human samples. MA3-046 has been succesfully used in western blot and ChIP applications. Immunogen is a synthetic peptide corresponding to residues 118-132 of human GCN5.

SAGA (Spt-Ada-Gen5 histone acetyltransferase complex) is a histoneacetylase complex which has Gcn5p as catalyst subunit and functions overlapping with the fundamental transcription factor TFIID which has Taf1p as catalyst subunit. However, SAGA and TFIID have different allotment and each accomplishes the important role in the transcription for Housekeeping gene group and Stress Responding gene group. Also, SAGA is a gigantic protein complex which is composed of Ada protein group (5 kinds), TBP related protein group (4 kinds), TAF protein group (5 kinds that also pertain to TFIID), and other protein groups (>6 kinds). As its molecular function, there is the chemical modification of histone, or the recruitment by direct interaction of transcription regulating factor on DNA, or the control of transcription starting reaction by TBP. Gcn5p that show histoneacetylase activity is one kind of the above-mentioned Ada protein group, and in the case of budding yeast it is composed of 439 amino acid residues.

Specifications

• Antigen: GCN5
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.05% sodium azide
• Gene Accession No.: Q92830
• Gene Symbols: KAT2A
• Immunogen: Synthetic peptide coupled to ovalbumin corresponding to amino acids 118-132 of human GCN5: CKCNGWKNPKPPTAP.
• Regulatory Status: RUO
• Gene ID (Entrez): 2648
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Clone: 2GC-2C11
• Conjugate: Unconjugated
• Gene: KAT2A
• Gene Alias: 1110051E14Rik; AAS104; ADA4; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; Gcn5l2; general control of amino acid synthesis 5-like 2; general control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2; Kat2a; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97; SWI9; YGR252W
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1