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GCOM1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988533
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Catalog No. Quantity
50-198-8533 100 μL
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Catalog No. 50-198-8533 Supplier Bioss Supplier No. BS8403R
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Description

Rabbit Polyclonal Antibody

MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.

Specifications

Antigen GCOM1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MYZAP
Gene Accession No. P0CAP1
Gene Alias AA407270; AV006038; gcom; GCOM1; Gcom2; Gm640; GRINL1A; GRINL1A combined protein; GRINL1A complex locus 1; GRINL1A complex locus protein 1; GRINL1A complex locus upstream; GRINL1A upstream protein; Grinl1a7; Gup; myocardial intercalated disc protein; Myocardial zonula adherens protein; myocardium-enriched ZO1-associated protein; myocardium-enriched zonula adherens protein; myocardium-enriched zonula occludens-1-associated protein; MYOZAP; MYZAP; MYZAP-POLR2M
Gene Symbols MYZAP
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GCOM1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100820829
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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