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Invitrogen™ GCP4 Monoclonal Antibody (GT812)
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Catalog No. PIMA517294
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100 μL
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PIMA517294 100 μL
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Catalog No. PIMA517294 Supplier Invitrogen™ Supplier No. MA517294
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Description

Mouse Monoclonal Antibody

Recommended positive controls: HeLa. Predicted reactivity: Mouse (97%), Zebrafish (90%), Xenopus laevis (90%), Rabbit (97%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCP4
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT812
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene TUBGCP4
Gene Accession No. Q9UGJ1
Gene Alias 4932441P04Rik; 76P; D2Ertd435e; gamma tubulin ring complex protein; gamma tubulin ring complex protein (76p gene); gamma-ring complex protein 76 kDa; Gamma-tubulin complex component 4; GCP4; GCP-4; Grip76; h76p; hGCP4; hGrip76; MCCRP3; RGD1306924; TUBGCP4; tubulin gamma complex associated protein 4; tubulin, gamma complex associated protein 4
Gene Symbols TUBGCP4
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the center region of human GCP4. The exact sequence is proprietary.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27229
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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