Invitrogen™ GCP4 Polyclonal Antibody

Catalog No.	Quantity
PIPA560279	100 μL

Catalog No. PIPA560279 Supplier Invitrogen™ Supplier No. PA560279

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ILFVGESVQM FENQNVNLTR KGSILKNQED TFAAELHRLK QQPLFSLVDF EQVVDRIRST VAEHLWKLMV EESDLLGQLK IIKDFYLLGR GELFQAFIDT AQHMLKTPPT A Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.

Specifications

• Antigen: GCP4
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TUBGCP4
• Gene Accession No.: Q9UGJ1
• Gene Alias: 4932441P04Rik; 76P; D2Ertd435e; gamma tubulin ring complex protein; gamma tubulin ring complex protein (76p gene); gamma-ring complex protein 76 kDa; Gamma-tubulin complex component 4; GCP4; GCP-4; Grip76; h76p; hGCP4; hGrip76; MCCRP3; RGD1306924; TUBGCP4; tubulin gamma complex associated protein 4; tubulin, gamma complex associated protein 4
• Gene Symbols: TUBGCP4
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human GCP4. Recombinant protein control fragment (Product #RP-98070).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27229
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG