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Invitrogen™ GCP5 Polyclonal Antibody
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Catalog No. PA550967
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100 μL
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PA550967 100 μL
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Catalog No. PA550967 Supplier Invitrogen™ Supplier No. PA550967
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Description

Rabbit Polyclonal Antibody

GCP5 / TUBGCP5 Polyclonal Antibody detects endogenous levels of GCP5 / TUBGCP5 protein.

The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complex associated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP5 ( gamma-Tubulin complex component 5), also known as TUBGCP5, is a 1, 024 amino acid member of the gamma-Tubulin complex and is highly expressed in heart and skeletal muscle. Defects in the gene encoding GCP5 are implicated in Prader-Willi syndrome (PWS), a rare genetic disorder associated with obesity, compulsive behavior and lower intellectual ability.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCP5
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
Gene Tubgcp5
Gene Accession No. Q8BKN5, Q96RT8
Gene Alias B130010C12Rik; Gamma-tubulin complex component 5; gamma-tubulin complex component GCP5; GCP5; GCP-5; KIAA1899; mKIAA1899; Tubgcp5; tubulin gamma complex associated protein 5; tubulin, gamma complex associated protein 5
Gene Symbols Tubgcp5
Host Species Rabbit
Immunogen Synthesized peptide derived from the Internal region of human GCP5 (aa 741-790).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114791, 233276, 308663
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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