Invitrogen™ GDF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103064

Catalog No. PIPA5103064

Description

Antibody detects endogenous levels of total GDF1.

Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.

Specifications

• Antigen: GDF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDF1
• Gene Alias: AI385651; DORV; DTGA3; Embryonic growth/differentiation factor 1; Gdf1; GDF-1; growth differentiation factor 1; RAI
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14559, 2657, 306351
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P20863, P27539
• Gene Symbols: GDF1
• Immunogen: A synthesized peptide derived from human GDF1(Accession P27539), corresponding to amino acid residues A52-V102.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG