Invitrogen™ GDF11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120001

Catalog No. PIPA5120001

Description

Positive Control: Hela, SW480, HepG2, human colon cancer tissue, mouse brain tissue. Subcellular Location: Secreted.

GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Specifications

• Antigen: GDF11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDF11
• Gene Alias: BMP11; BMP-11; bone morphogenetic protein 11; GDF11; GDF-11; growth differentiation factor 11; growth/differentiation factor 11
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10220, 14561, 29454
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O95390, Q9Z1W4, Q9Z217
• Gene Symbols: GDF11
• Immunogen: Recombinant protein within human bmp11 aa 200-407.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov