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Invitrogen™ GDF15 Monoclonal Antibody (12), Invitrogen™

Catalog No. PIMA543384
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PIMA543384 50 μL
PIMA543013 100 μL
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Catalog No. PIMA543384 Supplier Invitrogen™ Supplier No. MA543384
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Description

Mouse Monoclonal Antibody

Specificity: Human GDF15/MIC-1

GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GDF15
Applications ELISA
Classification Monoclonal
Clone 12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% trehalose, 0.02% Tween 80 and no preservative; pH 7.0
Gene Gdf15
Gene Accession No. Q99988
Gene Alias Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF
Gene Symbols Gdf15
Host Species Mouse
Immunogen Recombinant Human GDF15/MIC-1 Protein.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9518
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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