Invitrogen™ GDF3 Polyclonal Antibody, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 500P2351MG

Catalog No. 500P2351MG

Description

AA Sequence of recombinant protein: AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human GDF-3. Anti-Human GDF-3-specific antibody was purified by affinity chromatography employing an immobilized Human GDF-3 matrix. Sandwich ELISA: To detect Human GDF-3 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human GDF-3 (500-P235Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human GDF-3. Western Blot: To detect Human GDF-3 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human GDF-3 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

GDF3 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. The function of this protein is unknown, but expression studies suggest it may be involved in regulation of the adult lymphatic and erythroid systems and embryonic development.

Specifications

• Antigen: GDF3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDF3
• Gene Alias: C78318; ecat9; Gdf3; Gdf-3; growth differentiation factor 3; growth/differentiation factor 3; KFS3; MCOP7; MCOPCB6; RGD1564178; UNQ222/PRO248; VG-1-related protein 2; Vgr2; Vgr-2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9573
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q9NR23
• Gene Symbols: GDF3
• Immunogen: E.coli-derived Recombinant Human GDF-3.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody