Invitrogen™ GDNF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115279

Catalog No. PIPA5115279

Description

Antibody detects endogenous levels of total GDNF.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Specifications

• Antigen: GDNF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GDNF
• Gene Alias: AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14573, 2668
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P39905, P48540
• Gene Symbols: GDNF
• Immunogen: A synthesized peptide derived from human GDNF(Accession P39905), corresponding to amino acid residues P29-P79.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG