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Invitrogen™ GDNF Polyclonal Antibody
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Catalog No. PIPA124827
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200 μg
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Catalog No. Quantity
PIPA124827 200 μg
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Catalog No. PIPA124827 Supplier Invitrogen™ Supplier No. PA124827
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Description

Goat Polyclonal Antibody

Neutralization: The ND50 is 2.6 μg/mL. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GDNF
Applications Inhibition Assays, Neutralization
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene GDNF
Gene Accession No. P39905
Gene Alias AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Gene Symbols GDNF
Host Species Goat
Immunogen Recombinant human GDNF expressed in Escherichia coli.
Purification Method IgG fraction
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2668
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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