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GDNF Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980772
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100 μL
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50-198-0772 100 μL
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Catalog No. 50-198-0772 Supplier Bioss Supplier No. BS1024R
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Description

Rabbit Polyclonal Antibody

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson′s disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Specifications

Antigen GDNF
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene GDNF
Gene Accession No. P39905
Gene Alias AI385739; Astrocyte-derived trophic factor; ATF; ATF1; ATF2; Gdnf; glial cell derived neurotrophic factor; glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor; Glial cell line-derived neurotrophic factor; gndf; HFB1-GDNF; hGDNF; H-GDNF; HSCR3; mGDNF; neurotrophic factor
Gene Symbols GDNF
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GDNF.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2668
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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