Cytiva MabSelect Sure™ Chromatography Media

MabSelect™ SuRe™ is a protein A affinity medium for capturing MAbs at process scale with an alkali-tolerant rProtein A ligand that allows the for cost-effective sanitization protocols

Supplier:  Cytiva 17543802

Catalog No. 45-002-989

Description

Has an alkali-tolerant rProteain A ligand designed to enhance protease resistance to produce monoclonal antibodies

• Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH
• Design gives enhanced protease resistance resulting in lower ligand leakage
• Generic elution profile for different monoclonal antibodies enables platform approach to purification
• High-flow agarose matrix allows the processing of large feed volumes
• Used in the commercial manufacture of monoclonal antibodies

Specifications

• Quantity: 200 mL
• Stability: Stable in aqueous Buffers commonly used in Protein A Chromatography
• Binding Capacity: 30 mg Human lgG/mL (at 2.4 min. residence time)
• Flow Rate: <500 cm/Hoμr
• Height (English) Bed: 7.87 in.
• Includes: Certificate of Analysis
• Matrix: Highly Cross-Linked Agarose
• Storage Buffer: 20% Ethanol

• For Use With (Application): For Use of Rigorous and Cost-Effective CIP and Sanitization Protocols, Manufacture of Monoclonal Antibodies
• Storage Requirements: 2°C to 8°C
• Product Type: MabSelect SuRe Media
• Particle Size: 85 μm
• Height (Metric) Bed: 20 cm
• Max. Pressure: <200 kPa
• pH Range: 3 to 12
• Ligand Type: Alkali-stabilized Protein A-derived (E. coli)