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Tocris Bioscience™ GeA-69

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Quantity:
10 mg
50 mg
Description
GeA-69 is a selective allosteric inhibitor of poly (ADP-ribose) polymerase 14 (PARP14) macrodomain 2 (MD2) (IC50 = 720 nM, Kd = 860 nM). It inhibits adenosine diphosphate ribose (ADPR) binding to the macrodomain 2 of PARP14 and prevents PARP14 MD2 localization to DNA damage sites in intact cells. GeA-69 is highly cell permeable.
Specifications
Specifications
Chemical Name or Material | N-[2-(9 H-Carbazol-1-yl)phenyl]acetamide |
CAS | 2143475-98-1 |
Quantity | 50 mg |
Target | PARP |
Molecular Formula | C20H16N2O |
Purity | 0.98 |
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