Invitrogen™ GEF-H1 Monoclonal Antibody (K.607.1)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA515027

Catalog No. PIMA515027

Description

It is not recommended to aliquot this antibody.

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.

Specifications

• Antigen: GEF-H1
• Classification: Monoclonal
• Concentration: 33 μg/mL
• Formulation: 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: Q5FVC2, Q60875, Q92974
• Gene Symbols: ARHGEF2
• Immunogen: Synthetic peptide corresponding to the sequence of human GEF-H1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey, Hamster
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: K.607.1
• Conjugate: Unconjugated
• Gene: ARHGEF2
• Gene Alias: AA408978; ARHGEF2; CG10188; CG10188-PA; CG10188-PB; CG10188-PC; cyst; cyst-PA; cyst-PB; cyst-PC; cysts; DKFZp547L106; DKFZp547P1516; Dmel\CG10188; Dmel_CG10188; FLJ45440; GEF; GEFH1; GEF-H1; Guanine nucleotide exchange factor H1; Kiaa0651; Lbcl1; LBC'S first cousin; Lfc; LFP40; Lymphoid blast crisis-like 1; microtubule-regulated Rho-GEF; mKIAA0651; oncogene LFC; OTTHUMP00000018855; P40; Proliferating cell nucleolar antigen p40; rho guanine nucleotide exchange factor 2; rho guanine nucleotide exchange factor 2-like protein; Rho/Rac guanine nucleotide exchange factor (GEF) 2; Rho/Rac guanine nucleotide exchange factor 2; rhobin
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100758849, 16800, 310635, 9181
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov